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KMID : 0882420140860030319
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Korean Journal of Medicine
2014 Volume.86 No. 3 p.319 ~ p.324
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A Large Neuroendocrine Tumor of the Major Duodenal Papilla Removed by Endoscopic Papillectomy
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Bae Seung-Hyeon
Kim Jin-Yong
Kim Chang-Lae
Choi Young-Kwon
Shin Bo-Mi
Hong Seung-Mo
Kim Myung-Hwan
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Abstract
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Neuroendocrine tumors (NET) of the major duodenal papilla are rare and the natural history of this disease is not clear. We experienced a case in a 31-year-old male. Duodenoscopy revealed an enlarged major duodenal papilla with central umbilication and nodularity. Endoscopic ultrasonography (EUS) demonstrated a 3-cm hypoechoic mass that was confined to the submucosa. A biopsy led to the diagnosis of a grade 1 NET. The patient refused surgery, so we performed an endoscopic papillectomy. The tumor was removed completely. The resected specimen confirmed the diagnosis of a well-differentiated NET and all resection margins were negative. Surgical resection is currently considered to be the gold standard for the treatment of a large NET of the major duodenal papilla; however, endoscopic resection is a possible treatment modality for patients at high surgical risk or who are reluctant to undergo surgery.
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KEYWORD
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Neuroendocrine tumors, Major duodenal papilla
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